Pyruvate and Error! Bookmark not defined. Oxidative decarboxylation of-ketoglutarate in the nervous

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9 is one. Many of the coenzyme is the pioneer true value of intermediary metabolism enzymes. Are not toxic, they are stored in very small amounts. Are excreted in the urine when too much is taken. Must be so constant diet.
Pyruvate and Error! Bookmark not defined. Oxidative decarboxylation of-ketoglutarate in the nervous system, including in particular, plays a key role in energy metabolism in many cells. Dehydrogenase activity of these two reactions in the absence of thiamine with reduced ATP production, and cellular function is impaired. Diagnosis, erythrocyte transketolase activity increased with the addition of the TPP is important.
Beri-beri; There are infantile and adult form. Infantile tachycardia, vomiting, convulsions and death if untreated seen. Adult type, skin dryness, irritability, loss of strength in the muscles, thinking and progressive paralysis would bozuklıug. If you move to cardiomegaly and kr.kalp failure develops.
Wernicke-Korsakoff syndrome: primary thiamine deficiency in developed countries kr. is associated with alcoholism and inadequate dietary true value intake or absorption from the intestine is due to deterioration. WK syndrome develops in some alcoholics, apathy, memory loss and forward-backward movement of the eyeball is characterized by.
2 - Riboflavin (vit.b2): Biologically active forms of flavin mononucleotide (FMN) and flavinadenindinükleotid (FAD) is. 2 as reversible H + atom both receive and FADH2 by FMNH2 occurs. FMN and FAD, or reduction that catalyzes oxidation of a substrate is bound tightly true value to flavoenzim. Error! Bookmark not defined. -Amino acid oxidase, xanthine oxidase, glycerol-3-P dehydrogenase, succinate benzaldehyde. Acyl CoA benzaldehyde. Pyruvate benzaldehyde., Error! Bookmark not defined. -Ketoglutarate benzaldehyde. and NADH-benzaldehyde. acts as a coenzyme in the reaction.
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